BDBM667404 1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benzyl}-4- (1,1-dioxido-1,2-thiazolidine- 2-yl)piperidine::US11957671, Compound 224

SMILES O=S1(=O)CCCN1C1CCN(Cc2ccc(cc2)[C@H]2COc3cccnc3O2)CC1

InChI Key InChIKey=SNNXDFDRWUCBSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667404   

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandPNGBDBM667404(US11957671, Compound 224 | 1-{4-[(2S)-2,3-dihydro-...)
Affinity DataIC50: 0.130nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent