BDBM667976 (2R,3R,4S,5R,6R)-N-(3-bromo-5-methylphenyl)-4-(4-(2,3-difluoro-4- methylphenyl)-1H-1,2,3-triazol-1-yl)-N-((3S,4S)-1-formyl-4- hydroxypyrrolidin-3-yl)-5-hydroxy-6-(hydroxymethyl)-3- methoxytetrahydro-2H-pyran-2-carboxamide::US20240124427, Example 92

SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(C)c(F)c1F)C(=O)N([C@H]1CN(C[C@@H]1O)C=O)c1cc(C)cc(Br)c1

InChI Key InChIKey=CRUDOTDWKSACHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 667976   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM667976(US20240124427, Example 92 | (2R,3R,4S,5R,6R)-N-(3-...)
Affinity DataIC50: 19nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM667976(US20240124427, Example 92 | (2R,3R,4S,5R,6R)-N-(3-...)
Affinity DataIC50: 491nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent