BDBM668219 5-(2-chlorophenyl)-7-(trifluoromethyl)-3,5-dihydro-4H-pyrazolo[3,4-c][1,8]naphthyridin-4-one ::US20240124454, Compound 6

SMILES FC(F)(F)c1ccc2c3cn[nH]c3c(=O)n(-c3ccccc3Cl)c2n1

InChI Key InChIKey=RKCZOALZEMRPLU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668219   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Nanjing Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM668219(US20240124454, Compound 6 | 5-(2-chlorophenyl)-7-(...)
Affinity DataIC50: 50.1nMAssay Description:The brief introduction of the test principle: L-methionine and ATP can be converted into SAM, inorganic phosphate, and inorganic diphosphate under th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent