BDBM668227 5-(4-(difluoromethoxy)phenyl)-7-ethoxy-1-methyl-1,5-dihydro-4H-imidazo[4,5-c][1,8]naphthyridin-4-one ::US20240124454, Compound 14

SMILES CCOc1ccc2c3n(C)cnc3c(=O)n(-c3ccc(OC(F)F)cc3)c2n1

InChI Key InChIKey=WGPDBWSKXKWGDB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668227   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Nanjing Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM668227(US20240124454, Compound 14 | 5-(4-(difluoromethoxy...)
Affinity DataIC50: 46.4nMAssay Description:The brief introduction of the test principle: L-methionine and ATP can be converted into SAM, inorganic phosphate, and inorganic diphosphate under th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent