BDBM668228 5-(4-(difluoromethoxy)phenyl)-1-methyl-7-(trifluoromethyl)-1H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one ::US20240124454, Compound 15

SMILES Cn1cnc2c1c1ccc(nc1n(-c1ccc(OC(F)F)cc1)c2=O)C(F)(F)F

InChI Key InChIKey=QXXOZWAFAOBENU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668228   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Nanjing Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM668228(US20240124454, Compound 15 | 5-(4-(difluoromethoxy...)
Affinity DataIC50: 38.5nMAssay Description:The brief introduction of the test principle: L-methionine and ATP can be converted into SAM, inorganic phosphate, and inorganic diphosphate under th...More data for this Ligand-Target Pair
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Date in BDB:
7/9/2024
Entry Details
US Patent