BDBM668246 5-(2-chloro-3-fluorophenyl)-7-(trifluoromethyl)oxazolo[4,5-c][1,8]naphthyridin-4(5H)-one ::US20240124454, Compound 35

SMILES Fc1cccc(c1Cl)-n1c2nc(ccc2c2ocnc2c1=O)C(F)(F)F

InChI Key InChIKey=OXZCMJVIXYDJHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668246   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM668246(5-(2-chloro-3-fluorophenyl)-7-(trifluoromethyl)oxa...)
Affinity DataIC50: 49nMAssay Description:The brief introduction of the test principle: L-methionine and ATP can be converted into SAM, inorganic phosphate, and inorganic diphosphate under th...More data for this Ligand-Target Pair
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Date in BDB:
7/9/2024
Entry Details
US Patent