BDBM668248 5-(2,3-dichlorophenyl)-1-methyl-7-(trifluoromethyl)-1,5-dihydro-4H-imidazo[4,5-c][1,8]naphthyridin-4-one ::US20240124454, Compound 37

SMILES Cn1cnc2c1c1ccc(nc1n(-c1cccc(Cl)c1Cl)c2=O)C(F)(F)F

InChI Key InChIKey=JTXJAGBBATVZOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668248   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM668248(5-(2,3-dichlorophenyl)-1-methyl-7-(trifluoromethyl...)
Affinity DataIC50: 48.3nMAssay Description:The brief introduction of the test principle: L-methionine and ATP can be converted into SAM, inorganic phosphate, and inorganic diphosphate under th...More data for this Ligand-Target Pair
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Date in BDB:
7/9/2024
Entry Details
US Patent