BDBM668261 7-chloro-1-methyl-5-(2-(trifluoromethyl)pyridin-3-yl)-1,5-dihydro-4H-imidazo[4,5-c]quinolin-4-one ::US20240124454, Compound 47::US20240124454, Compound 47-P2

SMILES Cn1cnc2c1c1ccc(Cl)cc1n(-c1cccnc1C(F)(F)F)c2=O

InChI Key InChIKey=DTOLNJQRFMQKOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 668261   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM668261(7-chloro-1-methyl-5-(2-(trifluoromethyl)pyridin-3-...)
Affinity DataIC50: 23.3nMAssay Description:The brief introduction of the test principle: L-methionine and ATP can be converted into SAM, inorganic phosphate, and inorganic diphosphate under th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetS-adenosylmethionine synthase isoform type-2(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM668261(7-chloro-1-methyl-5-(2-(trifluoromethyl)pyridin-3-...)
Affinity DataIC50: 50.2nMAssay Description:The brief introduction of the test principle: L-methionine and ATP can be converted into SAM, inorganic phosphate, and inorganic diphosphate under th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent