BDBM668269 3-(1-methyl-4-oxo-7-(trifluoromethyl)-1,4-dihydro-5H-imidazo[4,5-c][1,8]naphthyridin-5-yl)benzonitrile ::US20240124454, Compound 52

SMILES Cn1cnc2c1c1ccc(nc1n(-c1cccc(c1)C#N)c2=O)C(F)(F)F

InChI Key InChIKey=YUYLSPVMRXCXHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668269   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Nanjing Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM668269(3-(1-methyl-4-oxo-7-(trifluoromethyl)-1,4-dihydro-...)
Affinity DataIC50: 47.2nMAssay Description:The brief introduction of the test principle: L-methionine and ATP can be converted into SAM, inorganic phosphate, and inorganic diphosphate under th...More data for this Ligand-Target Pair
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Date in BDB:
7/9/2024
Entry Details
US Patent