BDBM668345 (1S,3R)-3-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cycloheptanol ::US20240124469, Compound 21

SMILES O[C@H]1CCCC[C@H](C1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1

InChI Key InChIKey=NKKXUJQDSXSZIS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 668345   

TargetSerine/threonine-protein kinase pim-1(Human)
Hangzhou Biosun Pharmaceutical Co.

US Patent
LigandPNGBDBM668345(US20240124469, Compound 21 | (1S,3R)-3-[[3-[3-(tri...)
Affinity DataIC50: 550nMAssay Description:PIM1, PIM2, and PIM3 (all three kinases are from Carna) were each prepared with 1× Kinase buffer into a kinase solution at a concentration that was 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-3(Human)
Hangzhou Biosun Pharmaceutical Co.

US Patent
LigandPNGBDBM668345(US20240124469, Compound 21 | (1S,3R)-3-[[3-[3-(tri...)
Affinity DataIC50: 5.50E+3nMAssay Description:PIM1, PIM2, and PIM3 (all three kinases are from Carna) were each prepared with 1× Kinase buffer into a kinase solution at a concentration that was 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Hangzhou Biosun Pharmaceutical Co.

US Patent
LigandPNGBDBM668345(US20240124469, Compound 21 | (1S,3R)-3-[[3-[3-(tri...)
Affinity DataIC50: 5.50E+3nMAssay Description:PIM1, PIM2, and PIM3 (all three kinases are from Carna) were each prepared with 1× Kinase buffer into a kinase solution at a concentration that was 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent