BDBM668354 N-(7-cyclopropyl-7-azaspiro [3.5]nonan-2-yl)-3-(3-(trifluoromethyl)phenyl)imidazo[1,2-b]pyridazin-6-amine ::US20240124469, Compound 30

SMILES FC(F)(F)c1cccc(c1)-c1cnc2ccc(NC3CC4(C3)CCN(CC4)C3CC3)nn12

InChI Key InChIKey=YIMOMLGCFXFDAR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 668354   

TargetSerine/threonine-protein kinase pim-1(Human)
Hangzhou Biosun Pharmaceutical Co.

US Patent
LigandPNGBDBM668354(US20240124469, Compound 30 | N-(7-cyclopropyl-7-az...)
Affinity DataIC50: 55nMAssay Description:PIM1, PIM2, and PIM3 (all three kinases are from Carna) were each prepared with 1× Kinase buffer into a kinase solution at a concentration that was 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-3(Human)
Hangzhou Biosun Pharmaceutical Co.

US Patent
LigandPNGBDBM668354(US20240124469, Compound 30 | N-(7-cyclopropyl-7-az...)
Affinity DataIC50: 5.50E+3nMAssay Description:PIM1, PIM2, and PIM3 (all three kinases are from Carna) were each prepared with 1× Kinase buffer into a kinase solution at a concentration that was 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Hangzhou Biosun Pharmaceutical Co.

US Patent
LigandPNGBDBM668354(US20240124469, Compound 30 | N-(7-cyclopropyl-7-az...)
Affinity DataIC50: 1.00E+4nMAssay Description:PIM1, PIM2, and PIM3 (all three kinases are from Carna) were each prepared with 1× Kinase buffer into a kinase solution at a concentration that was 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent