BDBM66845 1-(2-fluorobenzyl)-6-keto-N-[3-(2-methoxyphenyl)propyl]nipecotamide::1-[(2-fluorophenyl)methyl]-N-[3-(2-methoxyphenyl)propyl]-6-oxidanylidene-piperidine-3-carboxamide::1-[(2-fluorophenyl)methyl]-N-[3-(2-methoxyphenyl)propyl]-6-oxo-3-piperidinecarboxamide::1-[(2-fluorophenyl)methyl]-N-[3-(2-methoxyphenyl)propyl]-6-oxopiperidine-3-carboxamide::MLS001072576::SMR000654749::cid_24790279

SMILES COc1ccccc1CCCNC(=O)C1CCC(=O)N(Cc2ccccc2F)C1

InChI Key InChIKey=WKBUIPWNFOKHOT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 66845   

TargetRho-associated protein kinase 2(Human)
Percipiad

US Patent
LigandChemical structure of BindingDB Monomer ID 66845BDBM66845(US12479866, Compound Netarsudil)
Affinity DataIC50: 6nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Percipiad

US Patent
LigandChemical structure of BindingDB Monomer ID 66845BDBM66845(US12479866, Compound Netarsudil)
Affinity DataIC50: 13nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Percipiad

US Patent
LigandChemical structure of BindingDB Monomer ID 66845BDBM66845(US12479866, Compound Netarsudil)
Affinity DataIC50: 29nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2026
Entry Details US Patent

TargetRho-associated protein kinase 1(Human)
Percipiad

US Patent
LigandChemical structure of BindingDB Monomer ID 66845BDBM66845(US12479866, Compound Netarsudil)
Affinity DataIC50: 102nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2026
Entry Details US Patent

TargetPRKR-interacting protein 1(Human)
Percipiad

US Patent
LigandChemical structure of BindingDB Monomer ID 66845BDBM66845(US12479866, Compound Netarsudil)
Affinity DataIC50: 322nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
Target InfoKEGG
GoogleScholar
In Depth
Date in BDB:
4/6/2026
Entry Details US Patent