BDBM668458 6-(1-Isopropyl-1H-pyrazol-3-yl)- N-((1S,3R)-3- methoxycyclopentyl)-2-(1- methyl-1H-imidazol-2-yl)-5- phenylthieno[2,3-d]pyrimidin-4- amine::US20240124483, Compound 11

SMILES CO[C@@H]1CC[C@@H](C1)Nc1nc(nc2sc(-c3ccn(n3)C(C)C)c(-c3ccccc3)c12)-c1nccn1C

InChI Key InChIKey=ZUGHJPSDDNMVOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668458   

TargetGTPase KRas [Q61H]/Son of sevenless homolog 1(Human)
Shy Therapeutics

US Patent
LigandPNGBDBM668458(6-(1-Isopropyl-1H-pyrazol-3-yl)- N-((1S,3R)-3- met...)
Affinity DataIC50: 3.00E+3nMAssay Description:The small GTPases proteins cdc42 and Rheb were expressed as His-tagged proteins. For the assay, the cdc42 and Rheb purified small GTPases proteins we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent