BDBM668459 US20240124483, Compound 12::rac-6-(1-Isopropyl-1H-pyrazol- 3-yl)-N-((1R,3S)-3- methoxycyclopentyl)-5-methyl- 2-(1-methyl-1H-imidazol-2- yl)thieno[2,3-d]pyrimidin-4- amine

SMILES CO[C@H]1CC[C@H](C1)Nc1nc(nc2sc(-c3ccn(n3)C(C)C)c(C)c12)-c1nccn1C

InChI Key InChIKey=YMEVDDOPZRYMQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668459   

TargetGTPase KRas [Q61H]/Son of sevenless homolog 1(Human)
Shy Therapeutics

US Patent
LigandPNGBDBM668459(rac-6-(1-Isopropyl-1H-pyrazol- 3-yl)-N-((1R,3S)-3-...)
Affinity DataIC50: 7.50E+3nMAssay Description:The small GTPases proteins cdc42 and Rheb were expressed as His-tagged proteins. For the assay, the cdc42 and Rheb purified small GTPases proteins we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent