BDBM668460 N-((1s,3s)-3- methoxycyclobutyl)-2-(1-(2- methoxyethyl)-1H-imidazol-2- yl)-6-(1-methyl-1H-pyrazol-3- yl)-5-phenylthieno[2,3- d]pyrimidin-4-amine::US20240124483, Compound 13

SMILES COCCn1ccnc1-c1nc(N[C@H]2C[C@H](C2)OC)c2c(c(sc2n1)-c1ccn(C)n1)-c1ccccc1

InChI Key InChIKey=VBPOFMZEJPSMEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668460   

TargetGTPase KRas [Q61H]/Son of sevenless homolog 1(Human)
Shy Therapeutics

US Patent
LigandPNGBDBM668460(N-((1s,3s)-3- methoxycyclobutyl)-2-(1-(2- methoxye...)
Affinity DataIC50: 3.00E+3nMAssay Description:The small GTPases proteins cdc42 and Rheb were expressed as His-tagged proteins. For the assay, the cdc42 and Rheb purified small GTPases proteins we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent