BDBM668482 US20240124487, Compound 22::US20240124487, Compound 23

SMILES COc1ccc(COC2CCc3cc(CCc4cc(OCCCn5c(C(O)=O)c(C)c6c(-c7c(C)n(C)nc27)c(Cl)ccc56)c2ccc(F)cc2c4)n(C)n3)cc1

InChI Key InChIKey=YQQNCYGMNMNMIY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 668482   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM668482(US20240124487, Compound 22 | US20240124487, Compou...)
Affinity DataKi:  0.0730nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM668482(US20240124487, Compound 22 | US20240124487, Compou...)
Affinity DataKi:  0.357nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent