BDBM668490 US20240124487, Compound 31::US20240124487, Compound 34

SMILES COCCn1nc4cc1CCc8cc(OCCCn3c(C(=O)O)c(C)c2c(c(Cl)ccc23)c5c(C)nn6CCOC(CC4)c56)c7ccc(F)cc7c8

InChI Key InChIKey=AVGLBEAEJWJJGC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 668490   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM668490(US20240124487, Compound 31 | US20240124487, Compou...)
Affinity DataKi:  0.0280nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM668490(US20240124487, Compound 31 | US20240124487, Compou...)
Affinity DataKi:  0.408nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent