BDBM668784 US11964953, Example 81.2::ethyl 2-[4-[4-amino-2-(4-fluoro-N-[2-amino-1-methyl-2-oxo-ethyl]anilino)thiazole-5-carbonyl]phenoxy]acetate (enantiomer 2)

SMILES CCOC(=O)COc1ccc(cc1)C(=O)c1sc(nc1N)N([C@@H](C)C(N)=O)c1ccc(F)cc1

InChI Key InChIKey=UOZBFVTWLOGTOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668784   

TargetDiacylglycerol kinase zeta(Human)
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US Patent
LigandPNGBDBM668784(ethyl 2-[4-[4-amino-2-(4-fluoro-N-[2-amino-1-methy...)
Affinity DataIC50: 10.1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
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Date in BDB:
7/12/2024
Entry Details
US Patent