BDBM669462 US11964990, Example 4

SMILES CC1(C)C[C@H]2OCCCOC[C@@H]3CN(CCN3CC2=C(C1)c1ccc(Cl)cc1)c1ccc(C(=O)NS(=O)(=O)c2cnc(OCC3(F)CCN(CC3)C3COC3)c(Cl)c2)c(c1)N1CCCOc2nc3[nH]ccc3cc12

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 669462   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM669462(US11964990, Example 4)
Affinity DataKi:  0.280nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM669462(US11964990, Example 4)
Affinity DataKi:  18.8nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent