BDBM669499 US11964990, Example 41

SMILES CO[C@H]1C[C@H](CNc2ccc(cc2N([O-])=O)S(=O)(=O)NC(=O)c2ccc(cc2N2CCCOc3nc4[nH]ccc4cc23)N2CCN3CC4=C(CC(C)(C)C[C@H]4OCCCOC[C@@H]3C2)c2ccc(Cl)cc2)C1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 669499   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM669499(US11964990, Example 41)
Affinity DataKi:  0.224nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM669499(US11964990, Example 41)
Affinity DataKi:  25.2nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent