BDBM669519 N-(2-(2,6-dioxopiperidin-3-yl)-1,3- dioxoisoindolin-5-yl)-2- (trifluoromethoxy)benzenesulfonamide::US20240132463, Compound 1

SMILES FC(F)(F)Oc1ccccc1S(=O)(=O)Nc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1

InChI Key InChIKey=RKAFYSIKAVFVPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 669519   

TargetProtein cereblon(Human)
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM669519(US20240132463, Compound 1 | N-(2-(2,6-dioxopiperid...)
Affinity DataIC50: 2nMAssay Description:In this competitive fluorescent polarization assay Cy5 conjugated lenalidomide analog (Cy5-O-Len)13 was used as a fluorescent probe. 6×His-CRBN-DDB1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent