BDBM669523 N-(2-(2,6-dioxopiperidin-3-yl)-1,3- dioxoisoindolin-5- yl)benzenesulfonamide::US20240132463, Compound 20

SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)c2cc(NS(=O)(=O)c3ccccc3)ccc12

InChI Key InChIKey=HLZCITRKGRESDX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 669523   

TargetProtein cereblon(Human)
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM669523(US20240132463, Compound 20 | N-(2-(2,6-dioxopiperi...)
Affinity DataIC50: 72nMAssay Description:In this competitive fluorescent polarization assay Cy5 conjugated lenalidomide analog (Cy5-O-Len)13 was used as a fluorescent probe. 6×His-CRBN-DDB1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent