BDBM669576 US20240132477, Example 14

SMILES CC(N1CCCCC1)C(=O)N(C)c1cc2nc([nH]c2cc1C)-c1n[nH]c2C[C@@]3(C)C[C@H]3Cc12

InChI Key InChIKey=QKWZOSUWXRAVEZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 669576   

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandPNGBDBM669576(US20240132477, Example 14)
Affinity DataIC50: 47nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent