BDBM669908 Production of 3-(3-{[(R)-4-ethyl-1,1-dioxide-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl]methyl}-4-methylphenyl)-3-(thiophen-2-yl)propanoic acid ::US20240132519, Compound 17

SMILES CC[C@@H]1CN(Cc2cc(ccc2C)C(CC(O)=O)c2cccs2)S(=O)(=O)c2ccccc2O1

InChI Key InChIKey=QAAHCJFANWDTNJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 669908   

LigandPNGBDBM669908(US20240132519, Compound 17 | Production of 3-(3-{[...)
Affinity DataIC50: 28nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent