BDBM669916 Production of 3-(5-acetyl-4-fluorothiophen-2-yl)-3-(3-{[(R)-4-ethyl-1,1-dioxide-3,4-dihydro-2H-pyrido[4,3-b][1,4,5]oxathiazepin-2-yl]methyl}-4-methylphenyl)-2,2-dimethylpropanoic acid ::US20240132519, Compound 49
SMILES CC[C@@H]1CN(Cc2cc(ccc2C)C(c2cc(F)c(s2)C(C)=O)C(C)(C)C(O)=O)S(=O)(=O)c2cnccc2O1
InChI Key InChIKey=HLKSVUXHGPEEIS-VGOKPJQXSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 669916
TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Human)
Senju Pharmaceutical Co.
US Patent
Senju Pharmaceutical Co.
US Patent
Affinity DataIC50: 0.310nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair