BDBM669928 US20240132519, Compound D2

SMILES CC[C@H]1CN(Cc2cc(ccc2C)C(c2ccc(s2)C(C)=O)C(C)(C)C(O)=O)S(=O)(=O)c2cnccc2O1

InChI Key InChIKey=HSUSGYADAICRPE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 669928   

LigandPNGBDBM669928(US20240132519, Compound D2)
Affinity DataIC50: 5.17nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent