BDBM670399 ((2S)-2-(((2R,3S,4R,5R)-5-(6-Chloro-4-(cyclopentylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)-1-((isobutyramido(methyl)(oxo)-λ6-sulfaneylidene)amino)-3-methoxy-1-oxopropan-2-yl)phosphonic Acid::US20240140980, Example 15::US20240140980, Example 16

SMILES COC[C@@](OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ncc2c(NC3CCCC3)nc(Cl)nc12)(C(=O)N=S(C)(=O)NC(=O)C(C)C)P(O)(O)=O

InChI Key InChIKey=DRZXGHJTMXLHKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 670399   

Target5'-nucleotidase(Human)
Teon Therapeutics

US Patent
LigandPNGBDBM670399(US20240140980, Example 16 | ((2S)-2-(((2R,3S,4R,5R...)
Affinity DataIC50: 0.780nMAssay Description:Activity of recombinant CD73 was measured by quantification of free phosphate using the Malachite Green detection system (R&D Systems #DY996). Test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2024
Entry Details
US Patent

Target5'-nucleotidase(Human)
Teon Therapeutics

US Patent
LigandPNGBDBM670399(US20240140980, Example 16 | ((2S)-2-(((2R,3S,4R,5R...)
Affinity DataIC50: 6.30nMAssay Description:Activity of recombinant CD73 was measured by quantification of free phosphate using the Malachite Green detection system (R&D Systems #DY996). Test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2024
Entry Details
US Patent