BDBM670685 (S)-5-((2-amino-3-chloropyridin-4-yl)thio)-2-(1-amino-6-ethynyl-1,3-dihydrospiro[indene-2,4′-piperidin]-1′-yl)-3-methylpyrimidin-4(3H)-one::US20240140931, Compound 299

SMILES Cn1c(ncc(Sc2ccnc(N)c2Cl)c1=O)N1CCC2(Cc3ccc(cc3[C@H]2N)C#C)CC1

InChI Key InChIKey=VYGPCBLZPJLGMQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670685   

LigandPNGBDBM670685((S)-5-((2-amino-3-chloropyridin-4-yl)thio)-2-(1-am...)
Affinity DataIC50: 1nMAssay Description:1. Reagents and MaterialsHuman full-length SHP2 recombinant protein: BPS Bioscience, Cat #79018;SHP2 substrate DiFMUP (1 mM): BPS Bioscience, Cat #79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent