BDBM670746 N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-indolin-3-yl]-3-piperidyl]-1,1-dioxo-thiane-4-carboxamide::US20240140933, Example 36

SMILES CCNc1cc(F)cc2c1NC(=O)C2(C)N1CCC[C@H](C1)NC(=O)C1CCS(=O)(=O)CC1

InChI Key InChIKey=CZAWSSWQLJHLFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670746   

LigandPNGBDBM670746(N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-...)
Affinity DataIC50: 101nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent