BDBM670773 (3S,4S)-1-[(3R)-7-(ethylamino)-5-fluoro-3-methyl-2-oxo-indolin-3-yl]-4-phenyl-piperidine-3-carboxamide and (3S,4S)-1-[(3S)-7-(ethylamino)-5-fluoro-3-methyl-2-oxo-indolin-3-yl]-4-phenyl-piperidine-3-carboxamide::US20240140933, Example 63A

SMILES CCNc1cc(F)cc2c1NC(=O)[C@]2(C)N1CC[C@@H]([C@@H](C1)C(N)=O)c1ccccc1

InChI Key InChIKey=NUJRFGVIQFFBNJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670773   

LigandPNGBDBM670773(US20240140933, Example 63A | (3S,4S)-1-[(3R)-7-(et...)
Affinity DataIC50: 22nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
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