BDBM670778 (R)-3-(3-(difluoromethoxy)phenyl)-1- (5-fluoropyridin-2-yl)-N-(3-methyl- 1,1-dioxidothietan-3-yl)-4,5,6,7- tetrahydro-1H-indazole-6- carboxamide::US20240140938, Example 4

SMILES CC1(CS(=O)(=O)C1)NC(=O)[C@@H]1CCc2c(C1)n(nc2-c1cccc(OC(F)F)c1)-c1ccc(F)cn1

InChI Key InChIKey=FHNWZQRMRZQUGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670778   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM670778(US20240140938, Example 4 | (R)-3-(3-(difluorometho...)
Affinity DataIC50: 5.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
US Patent