BDBM670807 (R)-3-(3-(difluoromethoxy)phenyl)- 1-isopropyl-N-(4-methyl-1,1- dioxidotetrahydro-2H-thiopyran-4- yl)-4,5,6,7-tetrahydro-1H-indazole- 6-carboxamide::US20240140938, Example 31

SMILES CC(C)n1nc(c2CC[C@H](Cc12)C(=O)NC1(C)CCS(=O)(=O)CC1)-c1cccc(OC(F)F)c1

InChI Key InChIKey=LDLXTSVAHNWBGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670807   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM670807(US20240140938, Example 31 | (R)-3-(3-(difluorometh...)
Affinity DataIC50: 24.7nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
US Patent