BDBM670809 (R)-3-(3-ethoxyphenyl)-1-isopropyl- N-(4-methyl-1,1-dioxidotetrahydro- 2H-thiopyran-4-yl)-4,5,6,7- tetrahydro-1H-indazole-6- carboxamide::US20240140938, Example 33

SMILES CCOc1cccc(c1)-c1nn(C(C)C)c2C[C@@H](CCc12)C(=O)NC1(C)CCS(=O)(=O)CC1

InChI Key InChIKey=BIWBVOVHIXLQAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670809   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM670809(US20240140938, Example 33 | (R)-3-(3-ethoxyphenyl)...)
Affinity DataIC50: 3.30nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
US Patent