BDBM67081 3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanoic acid [2-(3,4-dimethylanilino)-2-oxoethyl] ester::3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propionic acid [2-(3,4-dimethylanilino)-2-keto-ethyl] ester::MLS002157858::SMR001240340::[2-(3,4-dimethylanilino)-2-oxoethyl] 3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanoate::[2-[(3,4-dimethylphenyl)amino]-2-oxidanylidene-ethyl] 3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanoate::cid_4782538

SMILES Cc1ccc(NC(=O)COC(=O)CCc2c(C)nc3ncnn3c2C)cc1C

InChI Key InChIKey=KTVJZZDBABXCNG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 67081   

TargetHistone-lysine N-methyltransferase NSD2(Human)
K36 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 67081BDBM67081(US20250361235, Compound I-1)
Affinity DataIC50: 5.5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2026
Entry Details ArticleUS Patent