BDBM670819 (R)-3-(5-fluoro-2-(2,2,2- trifluoroethoxy)pyridin-4-yl)-1- isopropyl-N-(3-methyl-1,1- dioxidothietan-3-yl)-4,5,6,7- tetrahydro-1H-indazole-6- carboxamide::US20240140938, Example 43

SMILES CC(C)n1nc(c2CC[C@H](Cc12)C(=O)NC1(C)CS(=O)(=O)C1)-c1cc(OCC(F)(F)F)ncc1F

InChI Key InChIKey=BKIDTLHTGFKELK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670819   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM670819(US20240140938, Example 43 | (R)-3-(5-fluoro-2-(2,2...)
Affinity DataIC50: 14.1nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
US Patent