BDBM670861 (R)-3-(5-(difluoromethoxy)-2- fluorophenyl)-1-isopropyl-N-(3- methyl-1,1-dioxidothietan-3-yl)- 4,5,6,7-tetrahydro-1H-indazole-6- carboxamide::US20240140938, Example 82

SMILES CC(C)n1nc(c2CC[C@H](Cc12)C(=O)NC1(C)CS(=O)(=O)C1)-c1cc(OC(F)F)ccc1F

InChI Key InChIKey=YTVYNVXPGSCIMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670861   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM670861(US20240140938, Example 82 | (R)-3-(5-(difluorometh...)
Affinity DataIC50: 30.8nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
US Patent