BDBM670863 (R)-3-(2-chloro-5- (difluoromethoxy)phenyl)-1- isopropyl-N-(3-methyl-1,1- dioxidothietan-3-yl)-4,5,6,7- tetrahydro-1H-indazole-6- carboxamide::US20240140938, Example 84

SMILES CC(C)n1nc(c2CC[C@H](Cc12)C(=O)NC1(C)CS(=O)(=O)C1)-c1cc(OC(F)F)ccc1Cl

InChI Key InChIKey=DFOBDTRRVOXJJK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670863   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM670863(US20240140938, Example 84 | (R)-3-(2-chloro-5- (di...)
Affinity DataIC50: 7.92nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent