BDBM671010 US11976059, Example 44

SMILES CN1CCN(CC1)c1ccc(cc1)-c1ccc2CN([C@@H](c3cc4ccccc4[nH]3)c3cc(Cl)ccc3O)C(=O)c2c1

InChI Key InChIKey=NNCDRTFCWPACKA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 671010   

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM671010(US11976059, Example 44)
Affinity DataIC50: 190nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent