BDBM671011 US11976059, Example 45

SMILES Oc1ccc(F)cc1[C@@H](N1Cc2ccc(cc2C1=O)-c1ccc(cc1)N1CCOCC1)c1cc2ccccc2[nH]1

InChI Key InChIKey=BYVXUCRNDIDPMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 671011   

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM671011(US11976059, Example 45)
Affinity DataIC50: 280nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent