BDBM673704 Example 921A methyl (1s,4s)-2′-bromo-4-[(3-chlorophenyl)(trifluoroacetyl)amino]-5′-fluorospiro[cyclohexane-1,1′-indene]-4-carboxylate::US20240150293, Example 921

SMILES COCc1cc2c(C[C@H](C[C@@H](C)COc3ccnc4CCC[C@@H](C)c34)[C@]22CC[C@](CC2)(Nc2cccc(Cl)c2)C(O)=O)cc1F

InChI Key InChIKey=NFWQITUUQCJALT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673704   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM673704(US20240150293, Example 921 | Example 921A methyl (...)
Affinity DataKi:  0.0110nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent