BDBM674198 2,3,5-trifluoro-4-hydroxy-N- ({(1r,4r)-4-[6- (pyrimidin-2-yl)-2H- indazol-2-yl] cyclohexyl}methyl) benzamide::US20240150334, Example 27

SMILES O=C(NC[C@H]1CC[C@H](n2cc3ccc(-c4ncccn4)cc3n2)CC1)c1cc(F)c(O)c(F)c1F

InChI Key InChIKey=UTZBQKBMUAWYAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674198   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 674198BDBM674198(2,3,5-trifluoro-4-hydroxy-N- ({(1r,4r)-4-[6- (pyri...)
Affinity DataIC50: 2.70nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
US Patent