BDBM674230 3,5-difluoro-4- hydroxy-N-({(1r,4r)- 4-[6-(1-methyl-1H- pyrazol-4-yl)-2H- indazol-2-yl] cyclohexyl}methyl) benzamide::US20240150334, Example 60

SMILES Cn1cc(cn1)-c1ccc2cn(nc2c1)[C@H]1CC[C@H](CNC(=O)c2cc(F)c(O)c(F)c2)CC1

InChI Key InChIKey=AJDVYWYBIXRJAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674230   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674230(3,5-difluoro-4- hydroxy-N-({(1r,4r)- 4-[6-(1-methy...)
Affinity DataIC50: 7.80nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent