BDBM674266 3,5-difluoro-4- hydroxy-N-({(1r,4r)- [6-(1,3-thiazol-5-yl)- 2H-indazol-2- yl]cyclohexyl} methyl)benzamide::US20240150334, Example 96

SMILES O=C(NC[C@H]1CC[C@H](n2cc3ccc(-c4cncs4)cc3n2)CC1)c1cc(F)c(O)c(F)c1

InChI Key InChIKey=OAMWFNUZNDKYPJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674266   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 674266BDBM674266(3,5-difluoro-4- hydroxy-N-({(1r,4r)- [6-(1,3-thiaz...)
Affinity DataIC50: 4.80nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
US Patent