BDBM674472 Cbz-Phe-Phe-vinyl-2PyrNMe::US20240150396, Compound 12

SMILES C[n+]1ccccc1\C=C\[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=FJXWVAUWWYLARM-UHFFFAOYSA-O

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 674472   

TargetCruzipain(Trypanosoma cruzi)
Texas A&M University

US Patent
LigandPNGBDBM674472(Cbz-Phe-Phe-vinyl-2PyrNMe | US20240150396, Compoun...)
Affinity DataKi:  280nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetCruzipain(Trypanosoma cruzi)
Texas A&M University

US Patent
LigandPNGBDBM674472(Cbz-Phe-Phe-vinyl-2PyrNMe | US20240150396, Compoun...)
Affinity DataKi:  280nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetCruzipain(Trypanosoma cruzi)
Texas A&M University

US Patent
LigandPNGBDBM674472(Cbz-Phe-Phe-vinyl-2PyrNMe | US20240150396, Compoun...)
Affinity DataKi:  280nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetProcathepsin L(Human)
Texas A&M University

US Patent
LigandPNGBDBM674472(Cbz-Phe-Phe-vinyl-2PyrNMe | US20240150396, Compoun...)
Affinity DataKi:  700nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetCathepsin S(Human)
Texas A&M University

US Patent
LigandPNGBDBM674472(Cbz-Phe-Phe-vinyl-2PyrNMe | US20240150396, Compoun...)
Affinity DataKi:  870nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetCathepsin B(Human)
Texas A&M University

US Patent
LigandPNGBDBM674472(Cbz-Phe-Phe-vinyl-2PyrNMe | US20240150396, Compoun...)
Affinity DataKi:  1.90E+4nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent