BDBM674488 US20240150396, Compound 30 LL166

SMILES OC1Oc2ccccc2CC1NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=SHSWGVYDDDLDDL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 674488   

TargetProcathepsin L(Human)
Texas A&M University

US Patent
LigandPNGBDBM674488(US20240150396, Compound 30 LL166)
Affinity DataKi:  28nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetCruzipain(Trypanosoma cruzi)
Texas A&M University

US Patent
LigandPNGBDBM674488(US20240150396, Compound 30 LL166)
Affinity DataKi:  49nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetCathepsin B(Human)
Texas A&M University

US Patent
LigandPNGBDBM674488(US20240150396, Compound 30 LL166)
Affinity DataKi:  4.50E+3nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

US Patent
LigandPNGBDBM674488(US20240150396, Compound 30 LL166)
Affinity DataKi: >1.00E+4nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent