BDBM674493 US20240150396, Compound 35 LL322

SMILES COC(=O)c1ccc2OC(O)C(Cc2c1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=USAVTLIPWBYPKG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 674493   

TargetProcathepsin L(Human)
Texas A&M University

US Patent
LigandPNGBDBM674493(US20240150396, Compound 35 LL322)
Affinity DataKi:  10.8nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetCruzipain(Trypanosoma cruzi)
Texas A&M University

US Patent
LigandPNGBDBM674493(US20240150396, Compound 35 LL322)
Affinity DataKi:  18nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetCathepsin B(Human)
Texas A&M University

US Patent
LigandPNGBDBM674493(US20240150396, Compound 35 LL322)
Affinity DataKi:  670nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

US Patent
LigandPNGBDBM674493(US20240150396, Compound 35 LL322)
Affinity DataKi: >1.00E+4nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent