BDBM674495 US20240150396, Compound 42 BC666

SMILES CN1CCN(CC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc[nH]c1=O)C=O

InChI Key InChIKey=KEHDYFXOYPSDFQ-PMACEKPBSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 674495   

TargetCruzipain(Trypanosoma cruzi)
Texas A&M University

US Patent
LigandPNGBDBM674495(US20240150396, Compound 42 BC666)
Affinity DataKi:  2.10nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProcathepsin L(Human)
Texas A&M University

US Patent
LigandPNGBDBM674495(US20240150396, Compound 42 BC666)
Affinity DataKi:  2.30nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

US Patent
LigandPNGBDBM674495(US20240150396, Compound 42 BC666)
Affinity DataKi:  860nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent