BDBM674521 ((1R,4R,7R)-7-amino-2- azabicyclo[2.2.1]heptan-2-yl)(2-(4- (cyclopropylmethyl)-3-(piperidin- 3-yl)-4H-thieno[3,2-b]pyrrol-5-yl)- 7-methoxy-1-methyl-1H- benzo[d]imidazol-5-yl)methanone, ISOMER 1::US11981680, Example 17::US11981680, Example 9

SMILES COc1cc(cc2nc(-c3cc4scc(C5CCCNC5)c4n3CC3CC3)n(C)c12)C(=O)N1C[C@H]2CC[C@@H]1[C@@H]2N

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 674521   

TargetProtein-arginine deiminase type-4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM674521(US11981680, Example 17 | ((1R,4R,7R)-7-amino-2- az...)
Affinity DataIC50: 40nMAssay Description:Compounds were solubilized in 100% DMSO to achieve a10 mM compound concentration. Compound stock solutions were stored at RT. A series of dilutions w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetProtein-arginine deiminase type-4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM674521(US11981680, Example 17 | ((1R,4R,7R)-7-amino-2- az...)
Affinity DataIC50: 79nMAssay Description:Compounds were solubilized in 100% DMSO to achieve a10 mM compound concentration. Compound stock solutions were stored at RT. A series of dilutions w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent