BDBM674535 1-(3-(5-(5-((1R,4R,7R)-7-amino-2-azabicyclo[2.2.1]heptane-2-carbonyl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-2-yl)-4-(cyclopropylmethyl)-4H-thieno[3,2-b]pyrrol-3-yl)azetidin-1-yl)ethan-1-one::US11981680, Example 23

SMILES COc1cc(cc2nc(-c3cc4scc(C5CN(C5)C(C)=O)c4n3CC3CC3)n(C)c12)C(=O)N1C[C@H]2CC[C@@H]1[C@@H]2N

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674535   

TargetProtein-arginine deiminase type-4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM674535(1-(3-(5-(5-((1R,4R,7R)-7-amino-2-azabicyclo[2.2.1]...)
Affinity DataIC50: 55nMAssay Description:Compounds were solubilized in 100% DMSO to achieve a10 mM compound concentration. Compound stock solutions were stored at RT. A series of dilutions w...More data for this Ligand-Target Pair
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Date in BDB:
8/13/2024
Entry Details
US Patent