BDBM674538 ((1R,4R,7R)-7-amino- 2- azabicyclo[2.2.1]heptan- 2-yl)(2-(4- (cyclopropylmethyl)-2- (1H-pyrazol-4-yl)-4H- thieno[3,2-b]pyrrol-5- yl)-7-methoxy-1- methyl-1H- benzo[d]imidazol-5- yl)methanone::US11981680, Example 26

SMILES COc1cc(C(=O)N2C[C@H]3CC[C@@H]2[C@@H]3N)cc2nc(-c3cc4sc(-c5cn[nH]c5)cc4n3CC3CC3)n(C)c12

InChI Key InChIKey=XNQHVJOLKSRRLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674538   

TargetProtein-arginine deiminase type-4(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 674538BDBM674538(((1R,4R,7R)-7-amino- 2- azabicyclo[2.2.1]heptan- 2...)
Affinity DataIC50: 107nMAssay Description:Compounds were solubilized in 100% DMSO to achieve a10 mM compound concentration. Compound stock solutions were stored at RT. A series of dilutions w...More data for this Ligand-Target Pair
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Date in BDB:
8/13/2024
Entry Details
US Patent